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USP Column Recommendation

The United States Pharmacopeia (USP) is a standard source for many pharmaceutical methods and it specifies columns by packing materials rather than by manufacturer.

Find below a list of the recommended PSS columns suitable for methods listed with the USP.

USP NoUSP DescriptionMatching PSS Material
L20Dihydroxypropane groups chemically bonded to porous silica particles, 3 to 10µm in diameter.PROTEEMA
L21A rigid, spherical styrene-divinylbenzene copolymer, 5 to 10 µm in diameter.SDV
L22A cation group resin made of porous polystyrene gel with sulfonic acid groups, about 10 µm in size.MCX
L23An ion exchange resin made of porous polymethacrylate or polyacrylate gel with quaternary ammonium groups, about 10 µm in size.NOVEMA Max
L25Packing having the capacity to separate compounds with a MW range from 100 to 5 000 Da (as determined by polyethylene oxide), applied to neutral, anionic and cationic water-soluble polymers.SUPREMA
(100 Å)
L33Packing having the capacity to separate proteins by molecular size over a range of 4 000 to 400 000 Da. It is spherical, silica-based, and processed to provide pH stability.PROTEEMA 
(300 Å)
L37Polymethacrylate gel packing having the capacity to separate proteins by molecular size over a range of 2 000 – 40 000 Da MW.SUPREMA
(30 Å)
L38Methacrylate-based size exclusion packing for water-solubles.SUPREMA
L39Hydrophilic polyhydroxymethacrylate gel of totally porous spherical resinSUPREMA
L59Packing having the capacity to separate proteins by molecular weight over the range of 5 to 7 000 kDa. It is spherical (5 - 10µm), silica-based, and processed to provide hydrophilic characteristics and pH stability.PROTEEMA 
(300 Å)

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